Milordpiero
Nuovo Utente
- Registrato
- 19/2/08
- Messaggi
- 20.932
- Punti reazioni
- 1.452
" si rischiano modifiche al genoma "
- Creatore Discussione Milordpiero
- Data di inizio
- Registrato
- 29/3/09
- Messaggi
- 25.826
- Punti reazioni
- 3.143
BROWNSTONE » ARTICOLI DEL BROWNSTONE INSTITUTE » RICERCATORI ALLARMATI PER AVER TROVATO UNA CONTAMINAZIONE DEL DNA NEL VACCINO PFIZER
MARYANNE DEMASI 20 SETTEMBRE 2023 VACCINI 7 MINUTI DI LETTURA
CONDIVIDI | STAMPA | E-MAIL
Phillip Buckhaults, esperto di genomica del cancro e professore presso l'Università della Carolina del Sud, ha testimoniato davanti a una commissione ad hoc per gli affari medici del Senato della Carolina del Sud affermando che il vaccino mRNA della Pfizer è contaminato da miliardi di minuscoli frammenti di DNA.
Buckhaults, che ha un dottorato di ricerca in biochimica e biologia molecolare, ha affermato che “esiste un rischio molto reale” che questi frammenti di DNA estraneo possano inserirsi nel genoma di una persona e diventare un “elemento permanente della cellula”.
Ha detto che si tratta di un meccanismo plausibile per quello che potrebbe "causare alcuni degli effetti collaterali rari ma gravi come la morte per arresto cardiaco" nelle persone che hanno seguito la vaccinazione con mRNA.
Buckhaults non è un allarmista ed è stato riluttante a rendere pubbliche le sue scoperte per paura di spaventare la gente.
Lui stesso è stato vaccinato tre volte con il vaccino covid della Pfizer e lo ha consigliato a parenti e amici. Ha descritto la tecnologia della piattaforma mRNA come “rivoluzionaria” e ha affermato che il vaccino ha salvato molte vite.
"Sono un vero fan di questa piattaforma", ha detto Buckhaults al Senato. “Penso che abbia il potenziale per curare i tumori, credo davvero che questa piattaforma sia rivoluzionaria. Nel corso della tua vita, ci saranno vaccini mRNA contro gli antigeni del tuo cancro unico. Ma devono risolvere questo problema”.
Buckhaults è molto preoccupato per il “rischio teorico molto reale di cancro futuro in alcune persone, a seconda di dove questo pezzo estraneo di DNA finisce nel genoma, può interrompere un gene soppressore del tumore o attivare un oncogene”.
“Sono un po’ allarmato per la presenza di questo DNA nel vaccino… Il DNA è un dispositivo di memorizzazione delle informazioni di lunga durata. È ciò con cui sei nato, con cui morirai e lo trasmetterai ai tuoi figli. … Quindi le alterazioni del DNA… beh, rimangono”, ha detto.
Buckhaults believes the vaccines were deployed in good faith, but given the panic and urgency of the crisis, “there were a lot of shortcuts taken.” He puts it down to incompetence not malice, quoting Hanlon’s razor…
“…. which is never attribute malice to that which can be better explained by incompetence. There could be malice underneath, but I’m trying to see just incompetence to be gracious,” he told the Senate.
The initial production of Pfizer’s covid vaccine used a method called Polymerase Chain Reaction (PCR) to amplify the DNA template that was then used for production of the mRNA. This method, called PROCESS 1, can be used to make a highly pure mRNA product.
However, in order to upscale the process for large-scale distribution of the vaccine to the population for its “emergency authorisation” supply, Pfizer switched to a different method – PROCESS 2 – to amplify the mRNA.
PROCESS 2 used bacteria to make large quantities of “DNA plasmid” (circular DNA instructions), which would be used to make the mRNA. Hence, the final product contained both plasmid DNA and mRNA.
The switch from PROCESS 1 to PROCESS 2, ultimately resulted in the contamination of the vaccine (see red circles)
Pfizer tried to deal with the problem by adding an enzyme (DNAse) to chop up the plasmid into millions of tiny fragments.
But Buckhaults said it made the situation worse because the more fragments you have, the greater the chance that one of the fragments inserts itself into the genome and disrupts a vital gene.
“[Pfizer] chopped them up to try to make them go away, but they actually increased the hazard of genome modification in the process,” explained Buckhaults.
“I don’t think there was anything nefarious here, I just think it was kind of a dumb oversight,” he added. “They just didn’t think about the hazard of genome modification…it’s not all that expensive to add another process to get it out.”
A BMJ investigation found that batches of vaccine derived from PROCESS 2, were shown to have substantially lower mRNA integrity, and some say these vaccines have been associated with greater adverse events.
Buckhault’s research is not an outlier. Genomics expert Kevin McKernan has also reported plasmid DNA contamination in both Pfizer and Moderna bivalent covid-19 vaccines, in amounts that far exceeded the safety limit set by the FDA.
Normally, low levels of naked DNA in a vaccine would not be a problem because the bits of DNA are chewed up by tissue enzymes before they’ve had a chance to get inside cells. However, the DNA in Pfizer’s vaccine is not “naked.”
It is wrapped up in lipid nanoparticles (LNPs) – essentially fat globules – that help transport the genetic material (mRNA and plasmid DNA) inside the cells where the DNA can migrate to the nucleus and insert itself into the genome.
That’s why Buckhaults told the Senate that the FDA’s rules for safe levels of DNA in vaccines do not apply to the new mRNA platform technology.
“The fact that there is a regulatory threshold for the amount of DNA allowed in a vaccine is a throwback to an era when we were talking about [traditional] vaccines…but they inappropriately applied that regulatory limit to this new kind of vaccine where everything is encapsulated in this lipid nanoparticle — this was an inappropriate application of an old school regulation to a new kind of vaccine,” said Buckhaults.
“This is not terribly expensive to do these kinds of tests,” he added, “But there has to be a system where professors are not going to be penalised for producing results that are counter to what the party line is supposed to be.”
Senator Billy Garrett asked whether Buckhaults could test for DNA contamination in the new covid boosters that the Biden administration just recommended for all Americans aged 6 months or older.
“I would like to do that,” said Buckhaults. “It takes about three hours to check a vial of vaccine to see if it’s got this in it – about 100 bucks of reagents.”
“And I will not get the vaccine again myself unless I get a batch and find out that it’s free of DNA,” he added.
While the Senators offered to intervene if Buckhaults received any retribution or harassment in response to his testimony at the hearing, they did appear helpless in their ability to bring about meaningful change.
Senator Richard Cash said, “We are not going to have any authority over the FDA to force Pfizer to do something. I mean, that’s a federal issue.”
Buckhaults told the Senate that he emailed the FDA about the contamination problem but had not received a reply.
The FDA has been approached for comment.
Republished from the author’s Substack
Published under a Creative Commons Attribution 4.0 International License
For reprints, please set the canonical link back to the original Brownstone Institute Article and Author.
DONATE
Name *
First
Last
Email *
SUBSCRIBE
There are literally thousands of peer reviewed studies on vaccine hesitancy and how the government can overcome it. In sum,…
As a journalist, I cannot say much more than the best available facts suggest, but as has been clear for…
Taking a new Covid shot every winter has no empirical basis. The burden of proving effectiveness against death squarely rests…
Pfizer is now claiming that the Moderna patents, which Moderna sought to weaponize against Pfizer/BioNTech, are invalid because the technology…
In January 2021, in the absence of any human data in pregnancy, the CDC stated on its website that mRNA vaccines were…
Rutgers is one of a small minority of universities steadfastly holding onto COVID vaccine mandates. The pandemic is nowhere near…
BROWNSTONE INSTITUTE
2028 E BEN WHITE BLVD, #240-3088
AUSTIN, TX 78741
+1-469-842-8976
—
WEST HARTFORD, CT
Brownstone Institute è un'organizzazione no-profit 501(c)(3) registrata negli Stati Uniti con EIN: 87-1368060
© 2023 Tutti i diritti riservati
Progettazione, sviluppo e hosting di Shyfrog Media
Ricercatori allarmati per aver trovato una contaminazione del DNA nel vaccino Pfizer
DI MARYANNE DEMASI 20 SETTEMBRE 2023 VACCINI 7 MINUTI DI LETTURACONDIVIDI | STAMPA | E-MAIL
Phillip Buckhaults, esperto di genomica del cancro e professore presso l'Università della Carolina del Sud, ha testimoniato davanti a una commissione ad hoc per gli affari medici del Senato della Carolina del Sud affermando che il vaccino mRNA della Pfizer è contaminato da miliardi di minuscoli frammenti di DNA.
Buckhaults, che ha un dottorato di ricerca in biochimica e biologia molecolare, ha affermato che “esiste un rischio molto reale” che questi frammenti di DNA estraneo possano inserirsi nel genoma di una persona e diventare un “elemento permanente della cellula”.
Ha detto che si tratta di un meccanismo plausibile per quello che potrebbe "causare alcuni degli effetti collaterali rari ma gravi come la morte per arresto cardiaco" nelle persone che hanno seguito la vaccinazione con mRNA.
Buckhaults non è un allarmista ed è stato riluttante a rendere pubbliche le sue scoperte per paura di spaventare la gente.
Lui stesso è stato vaccinato tre volte con il vaccino covid della Pfizer e lo ha consigliato a parenti e amici. Ha descritto la tecnologia della piattaforma mRNA come “rivoluzionaria” e ha affermato che il vaccino ha salvato molte vite.
"Sono un vero fan di questa piattaforma", ha detto Buckhaults al Senato. “Penso che abbia il potenziale per curare i tumori, credo davvero che questa piattaforma sia rivoluzionaria. Nel corso della tua vita, ci saranno vaccini mRNA contro gli antigeni del tuo cancro unico. Ma devono risolvere questo problema”.
Buckhaults è molto preoccupato per il “rischio teorico molto reale di cancro futuro in alcune persone, a seconda di dove questo pezzo estraneo di DNA finisce nel genoma, può interrompere un gene soppressore del tumore o attivare un oncogene”.
“Sono un po’ allarmato per la presenza di questo DNA nel vaccino… Il DNA è un dispositivo di memorizzazione delle informazioni di lunga durata. È ciò con cui sei nato, con cui morirai e lo trasmetterai ai tuoi figli. … Quindi le alterazioni del DNA… beh, rimangono”, ha detto.
Buckhaults believes the vaccines were deployed in good faith, but given the panic and urgency of the crisis, “there were a lot of shortcuts taken.” He puts it down to incompetence not malice, quoting Hanlon’s razor…
“…. which is never attribute malice to that which can be better explained by incompetence. There could be malice underneath, but I’m trying to see just incompetence to be gracious,” he told the Senate.
How did the vials end up contaminated with DNA?
Buckhaults explained how two different manufacturing processes were used to make Pfizer’s vaccine.The initial production of Pfizer’s covid vaccine used a method called Polymerase Chain Reaction (PCR) to amplify the DNA template that was then used for production of the mRNA. This method, called PROCESS 1, can be used to make a highly pure mRNA product.
However, in order to upscale the process for large-scale distribution of the vaccine to the population for its “emergency authorisation” supply, Pfizer switched to a different method – PROCESS 2 – to amplify the mRNA.
PROCESS 2 used bacteria to make large quantities of “DNA plasmid” (circular DNA instructions), which would be used to make the mRNA. Hence, the final product contained both plasmid DNA and mRNA.
The switch from PROCESS 1 to PROCESS 2, ultimately resulted in the contamination of the vaccine (see red circles)
Pfizer tried to deal with the problem by adding an enzyme (DNAse) to chop up the plasmid into millions of tiny fragments.
But Buckhaults said it made the situation worse because the more fragments you have, the greater the chance that one of the fragments inserts itself into the genome and disrupts a vital gene.
“[Pfizer] chopped them up to try to make them go away, but they actually increased the hazard of genome modification in the process,” explained Buckhaults.
“I don’t think there was anything nefarious here, I just think it was kind of a dumb oversight,” he added. “They just didn’t think about the hazard of genome modification…it’s not all that expensive to add another process to get it out.”
A BMJ investigation found that batches of vaccine derived from PROCESS 2, were shown to have substantially lower mRNA integrity, and some say these vaccines have been associated with greater adverse events.
Buckhault’s research is not an outlier. Genomics expert Kevin McKernan has also reported plasmid DNA contamination in both Pfizer and Moderna bivalent covid-19 vaccines, in amounts that far exceeded the safety limit set by the FDA.
FDA safety limits
The FDA acknowledges that there are risks to having residual DNA left in vaccines:In its guidance to industry, the FDA says:
The problem with this advice said Buckhaults, is that it applies to the manufacturing of traditional vaccines, which contain what is known as “naked DNA.”
Normally, low levels of naked DNA in a vaccine would not be a problem because the bits of DNA are chewed up by tissue enzymes before they’ve had a chance to get inside cells. However, the DNA in Pfizer’s vaccine is not “naked.”
It is wrapped up in lipid nanoparticles (LNPs) – essentially fat globules – that help transport the genetic material (mRNA and plasmid DNA) inside the cells where the DNA can migrate to the nucleus and insert itself into the genome.
That’s why Buckhaults told the Senate that the FDA’s rules for safe levels of DNA in vaccines do not apply to the new mRNA platform technology.
“The fact that there is a regulatory threshold for the amount of DNA allowed in a vaccine is a throwback to an era when we were talking about [traditional] vaccines…but they inappropriately applied that regulatory limit to this new kind of vaccine where everything is encapsulated in this lipid nanoparticle — this was an inappropriate application of an old school regulation to a new kind of vaccine,” said Buckhaults.
What now?
Buckhaults said that vaccinated people need to be tested to see if any of the foreign DNA has integrated into the genome of their stem cells. This is easily detectable because the foreign DNA has a unique signature. Buckhaults said “It leaves a calling card.”“This is not terribly expensive to do these kinds of tests,” he added, “But there has to be a system where professors are not going to be penalised for producing results that are counter to what the party line is supposed to be.”
Senator Billy Garrett asked whether Buckhaults could test for DNA contamination in the new covid boosters that the Biden administration just recommended for all Americans aged 6 months or older.
“I would like to do that,” said Buckhaults. “It takes about three hours to check a vial of vaccine to see if it’s got this in it – about 100 bucks of reagents.”
“And I will not get the vaccine again myself unless I get a batch and find out that it’s free of DNA,” he added.
While the Senators offered to intervene if Buckhaults received any retribution or harassment in response to his testimony at the hearing, they did appear helpless in their ability to bring about meaningful change.
Senator Richard Cash said, “We are not going to have any authority over the FDA to force Pfizer to do something. I mean, that’s a federal issue.”
Buckhaults told the Senate that he emailed the FDA about the contamination problem but had not received a reply.
The FDA has been approached for comment.
Republished from the author’s Substack
Published under a Creative Commons Attribution 4.0 International License
For reprints, please set the canonical link back to the original Brownstone Institute Article and Author.
Author
- Maryanne Demasi
Maryanne Demasi, 2023 Brownstone Fellow, is an investigative medical reporter with a PhD in rheumatology, who writes for online media and top tiered medical journals. For over a decade, she produced TV documentaries for the Australian Broadcasting Corporation (ABC) and has worked as a speechwriter and political advisor for the South Australian Science Minister.
VIEW ALL POSTS
Donate Today
Your financial backing of Brownstone Institute goes to support writers, lawyers, scientists, economists, and other people of courage who have been professionally purged and displaced during the upheaval of our times. You can help get the truth out through their ongoing work.DONATE
Subscribe to Brownstone for More News
Name *
First
Last
Email *
SUBSCRIBE
Related Articles
Yes, You Are Being Manipulated
SEPTEMBER 19, 2023 / GOVERNMENT, VACCINESThere are literally thousands of peer reviewed studies on vaccine hesitancy and how the government can overcome it. In sum,…
Editor at “Pro-Vaccine Publication” Experienced Serious Adverse Event After Second Pfizer Shot
SEPTEMBER 12, 2023 / MEDIA, PHARMA, VACCINESAs a journalist, I cannot say much more than the best available facts suggest, but as has been clear for…
Get a New Covid Shot? The Evidence Suggests Otherwise
SEPTEMBER 5, 2023 / PUBLIC HEALTH, VACCINESTaking a new Covid shot every winter has no empirical basis. The burden of proving effectiveness against death squarely rests…
The Delights of the Pfizer/Moderna Catfight
SEPTEMBER 3, 2023 / PHARMA, VACCINESPfizer is now claiming that the Moderna patents, which Moderna sought to weaponize against Pfizer/BioNTech, are invalid because the technology…
Pfizer Drip Feeds Data From its Pregnancy Trial
AUGUST 28, 2023 / PHARMA, VACCINESIn January 2021, in the absence of any human data in pregnancy, the CDC stated on its website that mRNA vaccines were…
Rutgers Set to Disenroll Students on August 15th if Not Compliant with COVID Vaccine Mandates
AUGUST 14, 2023 / EDUCATION, VACCINESRutgers is one of a small minority of universities steadfastly holding onto COVID vaccine mandates. The pandemic is nowhere near…
Acquista Brownstone
- Felpa con cappuccio unisex Brownstone
$ 48,17 – $ 63,40
Seleziona le opzioni - Maglietta in cotone marrone pietra
$ 23,00 – $ 30,00
Seleziona le opzioni - CASA
- DI
- EVENTI
- ARTICOLI
- LIBRI
- SOTTOSCRIVI
- DONARE
- NEGOZIO
BROWNSTONE INSTITUTE
2028 E BEN WHITE BLVD, #240-3088
AUSTIN, TX 78741
+1-469-842-8976
—
WEST HARTFORD, CT
Brownstone Institute è un'organizzazione no-profit 501(c)(3) registrata negli Stati Uniti con EIN: 87-1368060
© 2023 Tutti i diritti riservati
Progettazione, sviluppo e hosting di Shyfrog Media