Spire Southampton Hospital in UK Celebrating Over 100 CHEMOSAT Treatments
GlobeNewswire•April 18, 2017
NEW YORK, April 18, 2017 (GLOBE NEWSWIRE) -- Delcath Systems, Inc. (DCTH), an interventional oncology company focused on the treatment of primary and metastatic liver cancers, commended Spire Southampton Hospital on the performance of over 100 percutaneous hepatic perfusion (PHP®) procedures with CHEMOSAT®. PHP with Melphalan/HDS was developed by Delcath Systems as a targeted, whole organ therapy for the liver. The product is commercially available in Europe under the trade name CHEMOSAT, and is being evaluated as an investigational therapy in the U.S. Delcath is currently enrolling patients in the FOCUS trial, a global Phase 3 clinical trial that is investigating PHP with Melphalan/HDS as a treatment for patients with ocular melanoma that has metastasized to the liver.
PHP is a minimally invasive procedure that isolates the liver from the body’s circulatory system, so that a high dose of chemotherapy (melphalan hydrochloride) may be infused directly into the liver with the potential to treat both visualized and non-visualized metastases. Blood from the liver is then filtered to remove the chemotherapeutic agent thereby minimizing systemic exposure and potentially the associated side effects.
As part of the Spire Southampton’s celebration of this milestone, a hospital statement highlighted the case of Brian Carney, a retired businessman from Leeds, UK. Mr. Carney was initially diagnosed with ocular melanoma in 2005, and in 2013 physicians discovered the disease had metastasized to his liver. Prognosis after ocular melanoma has metastasized in the liver is poor with a median survival of six months. In the case of Mr. Carney, he was referred to Spire Southampton, and received his first PHP treatment in December 2013. In the intervening period, he has also undergone liver resections and immunotherapy treatments. He recently became the first patient in the world to receive eight PHP treatments, which controlled the tumor and allowed him to conduct normal daily activities at his home. Mr. Carney remains under the care of Spire Southampton where his condition is regularly checked between therapies.
About Spire Southampton
Spire Southampton Hospital is a leading independent hospital group in the United Kingdom with 38 hospitals and 12 clinics across England, Wales and Scotland. The hospital is a leading CHEMOSAT-treatment center, performing the highest number of recorded PHP treatments in the world.